Benidipine calcium channel blocker promotes the death of cigarette smoke-induced senescent cells and improves lung emphysema

Alberta Palazzo (1) , Gabriela Makulyte (1) , Delphine Goerhig (1) , Jean-Jacques Médard (1) , Vincent Gros (2, 3) , François Trottein (4, 5) , Serge Adnot (2, 3) , David Vindrieux (1) , Jean-Michel Flaman (1) , David Bernard (1)

1 UNICANCER/CRCL - Centre de Recherche en Cancérologie de Lyon
2 Inserm U955 - Molecular virology and immunology – Physiopathology and therapeutic of chronic viral hepatitis (Team 18)
3 Hôpital Henri Mondor
4 Institut Pasteur de Lille
5 CIIL - Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204

Keywords: senolytic cigarette smoke lung disease cellular senescence calcium channel; senolytic; cigarette smoke; lung disease; cellular senescence; calcium channel

Domains: Cancer

Alberta Palazzo, Gabriela Makulyte, Delphine Goerhig, Jean-Jacques Médard, Vincent Gros, et al.. Benidipine calcium channel blocker promotes the death of cigarette smoke-induced senescent cells and improves lung emphysema. Aging (Albany N.Y.), 2023. ⟨hal-04373654⟩