A semi-automated Computer Tool for the Analysis of Retinal Vessel Diameter Dynamics

Guillaume Euvrard (1, 2) , Olivier Genevois (3) , Isabelle Rivals (1) , Pascale Massin (4) , Amélie Collet (5) , José-Alain Sahel (6) , Michel Paques (6)

1 ESA - Equipe de Statistique Appliquée (UMRS 1158)
2 ANAGOS
3 CHU Rouen
4 Centre Hospitalier Lariboisi ère
5 UPMC - Université Pierre et Marie Curie - Paris 6
6 Institut de la Vision

Retinal vessels are directly accessible to clinical observation. This has numerous potential interests for medical investigations. Using the Retinal Vessel Analyzer, a dedicated eye fundus camera enabling dynamic, video-rate recording of micrometric changes of the diameter of retinal vessels, we developed a semi-automated computer tool that extracts the heart beat rate and pulse amplitude values from the records. The extracted data enabled us to show that there is a decreasing relationship between heart beat rate and pulse amplitude of arteries and veins. Such an approach will facilitate the modeling of hemodynamic interactions in small vessels.

Keywords: Retinal Vessel Analyser; Pulse Amplitude; Heart Beat Rate; Signal Processing

Domains: Life Sciences [q-bio]; Human health and pathology; Cardiology and cardiovascular system; Engineering Sciences [physics]; Signal and Image processing; Computer Science [cs]; Signal and Image Processing

Guillaume Euvrard, Olivier Genevois, Isabelle Rivals, Pascale Massin, Amélie Collet, et al.. A semi-automated Computer Tool for the Analysis of Retinal Vessel Diameter Dynamics. Computers in Biology and Medicine, 2013, 43, pp.513-523. ⟨hal-00805371⟩