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Cyclosporin A Prevents the Hypoxic Adaptation by Activating Hypoxia-inducible Factor-1α Pro-564 Hydroxylation

Gisela D’angelo 1 Eric Duplan 2 Paul Vigne 2 Christian Frelin 2 
1 Biologie Cellulaire et Cancer
2 IPMC - Institut de pharmacologie moléculaire et cellulaire
Abstract : This is an Open Access article under the CC BY license.
Keywords : GST glutathione S-transferase HRE hypoxia-responsive elements ODD oxygen-dependent degradation PHD prolyl hydroxylase vHL von Hippel-Lindau Luc luciferase PBS phosphate-buffered saline
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Journal articles
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https://hal.archives-ouvertes.fr/hal-03424484
Contributor : Gisela D'ANGELO Connect in order to contact the contributor
Submitted on : Wednesday, November 10, 2021 - 3:22:27 PM
Last modification on : Thursday, August 4, 2022 - 4:57:42 PM
Long-term archiving on: : Friday, February 11, 2022 - 7:09:43 PM

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CNRS | FNCLCC | CURIE | UMR144 | PSL | UNIV-COTEDAZUR | SORBONNE-UNIVERSITE | SU-SCIENCES | SU-TI

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Gisela D’angelo, Eric Duplan, Paul Vigne, Christian Frelin. Cyclosporin A Prevents the Hypoxic Adaptation by Activating Hypoxia-inducible Factor-1α Pro-564 Hydroxylation. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2003, 278, pp.15406 - 15411. ⟨10.1074/jbc.m211293200⟩. ⟨hal-03424484⟩

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