Amorphous carbon nitride microband integrated in a microfluidic device for DNA biosensors applications - Labex MiChem Accéder directement au contenu
Article Dans Une Revue Journal of Electroanalytical Chemistry Année : 2021

Amorphous carbon nitride microband integrated in a microfluidic device for DNA biosensors applications

Résumé

This study presents the use of new kind of carbon electrode materials as ultramicroelectrodes (UMEs) in the field of electrochemical DNA biosensors which has already been proven to be effective in protocols to DNA sequences hybridization. In contrast to other carbon materials such as diamond like carbon, that are difficult to integrate in microfluidic devices due to their high temperature deposition, amorphous carbon nitride (a-CNx) is easily synthesized at room temperature on various materials using sputtering techniques. Here, we report a-CNx use as microband electrodes in Glass/PDMS microfluidic devices. a-CNx electrodes were activated and then biofuntionalized by covalent grafting of a DNA probe as self-assembled monolayer (SAM) with a view to future development of a detection platform targeting circulating DNA or RNA sequences in microfluidic channels.
Fichier principal
Vignette du fichier
manuscript_HAL.pdf (1.37 Mo) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-03242443 , version 1 (31-05-2021)

Identifiants

Citer

Marie-Charlotte Horny, Florence Billon, Claude Deslouis, Mathieu Lazerges, Vincent Dupuis, et al.. Amorphous carbon nitride microband integrated in a microfluidic device for DNA biosensors applications. Journal of Electroanalytical Chemistry, 2021, 895, pp.115395. ⟨10.1016/j.jelechem.2021.115395⟩. ⟨hal-03242443⟩
127 Consultations
285 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More