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Surface Force Measurements Using Brownian Particles

Abstract : Brownian motion in confinement and at interfaces is a canonical situation, encountered from fundamental biophysics to nanoscale engineering. Using the Lorenz-Mie framework, we optically record the thermally-induced tridimensional trajectories of individual microparticles, within water, and in the vicinity of a rigid wall. Based on this data, we implement a novel, robust and self-calibrated multifitting method, allowing for the thermal-noise-limited inference of spatially-resolved diffusion coefficients, equilibrium potentials, and forces -- at the femtoNewton resolution.
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Contributor : Thomas Salez <>
Submitted on : Tuesday, December 8, 2020 - 4:46:01 PM
Last modification on : Friday, December 11, 2020 - 3:31:19 AM


  • HAL Id : hal-03047058, version 1
  • ARXIV : 2012.05512



Maxime Lavaud, Thomas Salez, Yann Louyer, Yacine Amarouchene. Surface Force Measurements Using Brownian Particles. 2020. ⟨hal-03047058⟩



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