Skip to Main content Skip to Navigation
Journal articles

Controlling light in scattering media non-invasively using the photoacoustic transmission matrix

Abstract : Optical wavefront shaping has emerged as a powerful tool for manipulating light in strongly scattering media. It enables diffraction-limited focusing and imaging at depths where conventional microscopy techniques fail. However, to date, most examples of wavefront shaping have relied on direct access to the targets or implanted probes, and the challenge is to apply it non-invasively inside complex samples. Recently, ultrasonic-tagging techniques have been utilized successfully, but these allow only small acoustically tagged volumes to be addressed at each measurement. Here, we introduce an approach that allows the non-invasive measurement of an optical transmission matrix over a large volume, inside complex samples, using a standard photoacoustic imaging set-up. We demonstrate the use of this matrix for detecting, localizing and selectively focusing light on absorbing targets through diffusive samples, as well as for extracting the scattering medium properties. Combining the transmission-matrix approach with the advantages of photoacoustic imaging opens a path towards deep-tissue imaging and light delivery utilizing endogenous optical contrast.
Complete list of metadatas

https://hal.archives-ouvertes.fr/hal-01974506
Contributor : Thomas Chaigne <>
Submitted on : Thursday, December 10, 2020 - 9:54:40 PM
Last modification on : Saturday, December 19, 2020 - 3:42:11 AM

File

1305.6246.pdf
Files produced by the author(s)

Identifiers

Citation

T. Chaigne, O. Katz, A. Boccara, M. Fink, E. Bossy, et al.. Controlling light in scattering media non-invasively using the photoacoustic transmission matrix. Nature Photonics, Nature Publishing Group, 2014, 8 (1), pp.58-64. ⟨10.1038/nphoton.2013.307⟩. ⟨hal-01974506⟩

Share

Metrics

Record views

21

Files downloads

13